Hepatoprotectors - drugs for the treatment of the liver, the best drugs, pills. Overview of modern drugs for the treatment of the liver: effective, inexpensive drugs to restore a diseased organ Medicines that support the liver

To eliminate liver diseases, special medicines are used. Consider the most popular and effective drugs, their types, indications for use and cost.

Medicines for the liver are called hepatoprotectors, they are prescribed by the attending physician to eliminate violations of the functioning of the organ. They are necessary for the restoration of organ cells during long-term antibacterial or anti-tuberculosis therapy, the use of painkillers, antitumor and other drugs.

Faced with the problem of choosing a drug, patients are interested in the same questions. Which remedy is better, more effective, safer and cheaper? To date, there are many hepatoprotectors on the pharmaceutical market, which are used both for treatment and restoration of the organ:

• Phospholipids.
• Herbal remedies.
• Derivatives of amino acids.
• Bile acids.
• Homeopathic preparations.
• Biologically active additives.
• Medicines of animal origin.

All drugs have different effects on the body and have different effectiveness. Focusing on the results of diagnostics and tests, the symptoms and severity of the disease, the doctor selects the medicine.

The largest gland in the human body is the liver. The body performs many important functions: it participates in digestion, accumulates blood and glucose, neutralizes toxins and harmful substances, produces hormones and enzymes, cholesterol, bilirubin. The slightest violations in its functioning negatively affect the well-being of a person.

Medicines for the treatment of the liver are used to eliminate various diseases and repair damaged cells. Consider the most popular of them:

1. Herbal hepatoprotectors

Available in the form of capsules and enteric-coated tablets. In this category, drugs have proven themselves well, which include silymarin, which has a pronounced healing effect:

• Karsil - tablets with active ingredient - fruits of dry milk thistle.
• Gepabene - capsules with an extract of medicinal fumes and milk thistle.
• Silimar - tablets with dry milk thistle extract and other substances.

They have a minimal toxic effect on the body.

1. Essential phospholipids

Medicines are used in the treatment and prevention of cirrhosis, fatty degeneration, chronic, toxic and alcoholic hepatitis, radiation syndrome. The drugs are components of the cell wall of hepatocytes. They penetrate into the lipid layer of damaged cells and improve their functioning.

Taking the medicine minimizes energy costs, increases the enzymatic activity and physicochemical properties of bile. To achieve a stable therapeutic effect, long-term use is necessary, preferably intravenous administration. The most popular medicine from this group is Essentiale and Essentiale Forte N.

1. Biologically active additives

Many patients are convinced that nutritional supplements and various dietary supplements are absolutely safe and can be taken without medical permission. But this is not the case, some additives have hepatotoxic properties and, when interacting with other drugs, cause many side effects. Dietary supplements are not used as the main means, they are used in complex therapy or as an auxiliary medicine.

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Indications for the use of drugs for the liver

The use of any medication is possible only with the appropriate medical permission. Indications for the use of drugs for the liver depend on the severity of the underlying disease and the presence of concomitants, the age of the patient and other characteristics of the organism. To date, there are many hepatoprotectors that are prescribed in such cases:

• Hepatitis - most often prescribed to eliminate viral hepatitis, when antiviral agents did not have the expected result or such therapy is impossible. Hepatoprotectors are used both in complex treatment and for the prevention of the disease.
• Fatty degeneration - occurs in patients with type 2 diabetes and obese patients. In such patients, fat cells form in the liver, which disrupt its normal functioning. For treatment, hepatoprotectors, cholesterol-lowering agents, antidiabetic drugs, diet and physical activity are prescribed.
• Alcoholic hepatitis with a risk of cirrhosis - before starting treatment, it is necessary to completely abandon alcohol, since pharmaceuticals will not give a therapeutic effect. If alcohol intake continues, then no drugs will help restore the diseased organ.
• Toxic, medicinal hepatitis - medicines not only eliminate the symptoms of the disease, but also help restore the body. A prerequisite for recovery is the elimination of factors that provoked malaise.

It must be understood that it is difficult to completely restore the health of the liver only with drugs, so the patient is prescribed a special diet, physiotherapy, mandatory treatment of the pancreas and gallbladder, that is, the organs involved in digestion.

Medications to treat cirrhosis of the liver

One of the dangerous diseases that is practically not treatable is cirrhosis. The choice of the method of therapy and the drug depends on the stage and activity of the pathological process. To date, there are no such means that could completely eliminate the disease. Medicines are aimed at correcting possible complications and protecting the organ from further destruction.

Medications for cirrhosis of the liver:

• Inactive form - with compensated cirrhosis, vitamin preparations are used for treatment. As a rule, patients are prescribed vitamin-mineral complexes: Alphabet, Vitrum, Duovit, Biomax.
• Cirrhosis of moderate activity - patients are prescribed herbal and vitamin remedies. This is a vitamin complex of group B, vitamin C, rutin, folic and lipoic acid. Of the medicines, preference is given to preparations based on milk thistle and artichoke.
• Decompensated cirrhosis - at this stage, various complications appear. For therapy, lipoic acid is used, which is used orally / intravenously and various hepatoprotectors.
• Cirrhosis complicated by ascites - the patient is prescribed diuretics: Spironolactone, Furosemide, Triampur.
• Cryptogenic cirrhosis is the most dangerous form of the disease. For the treatment of pathology with an unknown cause, hepatoprotectors, herbal remedies, amino acid derivatives and other medicines are used.
• Viral cirrhosis - treatment is based on correcting the underlying disease. Most often, patients are prescribed Prednisolone. Dosage and duration of therapy is selected individually.

In the treatment of cirrhosis, not only drug therapy is necessary, but also diet, complete cessation of smoking and alcohol. If the pathology is detected in the early stages, then the liver can be restored.

Release form

The effectiveness of the drug is determined not only by its composition, but also by the form of release. Medicines for the liver are available in this form:

• Pills.
• Enteric-coated capsules.
• Powders for the preparation of solutions for oral administration.
• Ampoules for injection (drip and intravenous administration).
• Drops (for young children).
• Teas, phytocomplexes.

The doctor prescribes the most appropriate form of release, focusing on the course of the disease and the age of the patient.

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Pharmacodynamics

The effectiveness of a drug is determined by its biochemical properties. Pharmacodynamics provides information about the pharmacological group of the drug, its composition and indications for use. Consider these characteristics on the example of different groups of drugs prescribed for the treatment of liver diseases.

• Herbal hepatoprotectors

The active ingredients of Gepabene are extracts of medicinal plants. The active ingredient silymarin is derived from milk thistle fruit. It has a choleretic effect, normalizes the tone of the biliary tract and the amount of bile, improving its outflow into the intestines. Improves the function of protein formation, stabilizes hepatocyte membranes.

• Essential phospholipids

Essentiale is a highly purified fraction of phosphatidylcholine. The active ingredients are soybean phospholipids, which are similar in structure to the elements of hepatocytes. The lack of these substances leads to a violation of fat metabolism and the development of fatty degeneration. The medicine restores cellular structures, accelerates the regeneration process and slows down the formation of connective tissue.

Hepatosan is a drug with freeze-dried porcine liver cells. It enhances the detoxification function, absorbs and removes toxins, accelerates the regeneration of hepatocytes. It has two phases of action: intestinal and metabolic. At the first stage, detoxification of toxic substances in the intestine occurs, and at the second, biological components restore the functional activity of the damaged organ. The composition of the product includes vitamins, essential phospholipids, enzymes, amino acids.

• Amino acids

Ursosan is a hepatoprotector with a choleretic effect. Available in the form of capsules for oral use with the active substance ursodeoxycholic acid. Forms non-toxic mixed micelles with toxic bile acids, preventing damage to hepatocyte cell membranes. Reduces the amount of cholesterol in bile, promotes its absorption and excretion. Dissolves cholesterol gallstones and prevents the formation of new ones. The active component slows down the aging process and death of hepatocytes.

• Biologically active additives

Liv 52 is a combined drug with hepatoprotective, anti-inflammatory, choleretic and antitoxic effects. Improves the process of digestion and assimilation of food. Restores liver cells, minimizes any degenerative changes and enhances intracellular metabolism. Normalizes the level of bilirubin and other liver enzymes, improves the colloidal properties of bile and prevents stone formation.

Pharmacokinetics

For the treatment of diseases of the gastrointestinal tract, various drugs are used, which differ not only in their composition, but also in the forms of release. Pharmacokinetics allows you to learn about the processes of absorption and metabolism of the drugs used.

• Herbal hepatoprotectors

The active substance Gepabene is practically insoluble in water, forms salts with alkalis. If the drug enters the intestines, it is absorbed into the blood with split intestinal bacteria. The maximum concentration in plasma when taken orally is reached in 2 hours. Metabolites are excreted in the bile. The half-life is 5-6 hours.

• Essential phospholipids

About 90% of the taken dose of Essentiale is absorbed in the small intestine. The active ingredients are cleaved by phospholipase A to 1-acyl-lysophosphatidylcholine. Half of the resulting substance undergoes reverse acetylation during absorption in the intestinal mucosa. The maximum plasma concentration is reached within 6-24 hours after application. Excreted as metabolites in feces and urine.

• Animal products

Hepatosan is produced in the form of enteric-coated capsules for oral administration. After entering the body, the active substances quickly spread throughout the body, providing a therapeutic effect. Excreted as metabolites in the urine.

• Amino acids

Ursosan is absorbed from the small intestine and ileum. The concentration of the active substance in the blood plasma depends on the dose taken. Plasma protein binding is high, ursodeoxycholic acid crosses the placental barrier. Metabolized in the liver, excreted in bile, feces and urine.

• Biologically active additives

The pharmacokinetic properties of Liv 52 are due to the combined action of its active components.

Use of liver medications during pregnancy

Pregnancy is not only a long-awaited period for every woman, but also quite responsible. During gestation, the work of some organs and systems is disrupted, but the liver most often suffers. The process of blood supply is disturbed, which negatively affects the liver functionality. This process is considered natural, since after childbirth, the work of the body is restored. But expectant mothers may experience an exacerbation of chronic diseases that require treatment.

Consider drugs for the liver during pregnancy, which are used to prevent and eliminate pathological conditions:

• Essentiale Forte is a complex remedy with phospholipids that improves the cell membranes of a damaged organ. Consists of natural ingredients that do not penetrate the placental barrier. Can be used in any trimester.

• Legalon is a herbal medicine with the active ingredient milk thistle. It has a strong hepatoprotective effect, improves intracellular metabolism, stabilizes hepatocyte membranes. It is used to treat many diseases, regardless of etiology and severity.

• Karsil is one of the most popular medicines for repairing a weakened or damaged liver. The active ingredient is milk thistle extract. Used during pregnancy and for pediatric patients. Well tolerated, not addictive.

• Heptral is a hepatoprotective agent with the active substance ademetionine. It has a regenerating, detoxifying, antioxidant and neuroprotective effect. Effective in the treatment of toxic, viral and inflammatory liver lesions.
• Hofitol is a combined agent with choleretic, diuretic and hepatoprotective properties. The active ingredient is artichoke extract. It is used in chronic and acute course of diseases of the liver and organs.

Treatment of any diseases in expectant mothers has certain difficulties, since many drugs are contraindicated for use. The use of drugs for the liver during pregnancy is possible only for medical purposes. This is due to the fact that the active substances can penetrate the placental barrier, adversely affecting the development of the fetus.

A woman is selected safe drugs, usually plant-based. Many hepatoprotectors not only restore the functioning of the liver and digestive tract, but also alleviate the condition of a pregnant woman with toxicosis.

Contraindications for use

Medicines have not only indications, but also contraindications for use. Consider the prohibitions on the use of drugs to restore hepatocytes.

• Herbal hepatoprotectors

Gepabene is not allowed to be used in acute diseases of the liver and bile ducts, with intolerance to the components of the drug and for the treatment of patients under six years of age.

• Essential phospholipids

Essentiale is prohibited in case of hypersensitivity to its active substances. The solution for injection is not prescribed to newborns and premature babies, since benzyl alcohol is included in the composition of the product.

• Animal products

Hepatosan has the only contraindication - intolerance to the active components.

• Amino acids

Ursosan is not prescribed to patients with acute inflammatory lesions of the bile ducts and gallbladder, as well as in violation of contractile function. Tablets are not prescribed for calcified stones and biliary colic, impaired renal and liver function. The use of the drug in pediatric practice is possible for patients older than 5 years.

• Biologically active additives

Liv 52 is not used for intolerance to its components, during pregnancy and lactation. It is used with extreme caution in diseases of the gastrointestinal tract and for the treatment of children with pathologies of the biliary tract.

Side effects

Non-compliance with medical recommendations for the use of tablets leads to undesirable effects. Side effects of drugs for the liver are manifested by many organs and systems. Most often, these are allergic reactions: skin itching, rash, redness.

Gastrointestinal and cardiovascular disorders are possible. Patients complain of headaches, dizziness. Most hepatoprotectors and essential phospholipids are well tolerated, but only if the prescribed dosage and duration of therapy are observed.

Medicines for the liver after alcohol

Alcohol destroys liver cells not only in chronic alcoholics, but also in those who like to drink alcohol from time to time. But the situation is fixable, since the body has the ability to recover. There are many medicines that will help normalize the functioning of the liver and accelerate the regeneration of damaged cells.

The best medicines for the liver after alcohol:

• Restoring - this category includes hepatoprotectors, agents with essential phospholipids. Most often used: Essentiale, Phosphogliv, Essliver.
• Preparations (catalysts) for activating regeneration are vitamin complexes with amino acids that create an environment for the formation of new hepatocytes. This category includes: D i Guard, Dipana.
• Cleansers - facilitate the work of the body, remove toxins and eliminate signs of intoxication. Patients are prescribed: Karsil, Gepabene, Heptral, Silimar.

All of the above medicines can be used only for medical purposes. After diagnosing the patient's condition, the doctor selects the optimal medicine, determines the required dosage and duration of therapy. But the main rule of treatment after alcohol damage is a complete rejection of alcohol.

Medicines to restore the liver

Many drugs are used to restore the liver. They may have a plant base, animal liver enzymes, or amino acids and essential phospholipids. There are also combined means of complex action. It is impossible to name the best remedy, because for each case there is an optimal drug.

Medications to restore the liver:

• Biologically active additives - Artichoke extract, Heptralight, Liposil, Hepatrin.
• Tablets and capsules - Enerliv, Essliver forte, Karsil, Liv 52.
• Homeopathic remedies - Galsten drops, Hepel tablets.

For recovery, you can use not only pharmacological agents, but also methods of traditional medicine. For example, aromatherapy with anise, rosemary, juniper and other essential oils. The recipe for pumpkin with honey is especially popular and has a healing effect. A ripe vegetable must be washed, cut off the top and cleaned the seeds. Pour honey inside and close with a cut top. Leave the vegetable to infuse at room temperature or in a cool place for 10 days. After this period, drain the honey and take 1 spoon 2-3 times a day. The course of such therapy is 1-2 months.

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Medicines for liver cleansing

Many people face such a problem as liver disease. The main filter of the body ceases to fully cope with its functions, causing disturbances from other organs and systems. To eliminate the pathological condition, as a rule, plant-based preparations are used. Such tools allow you to adjust the enzyme activity, minimize the effects of toxins and increase resistance to the negative effects of harmful substances.

The main list of drugs for cleansing the liver:

• HeptraLight - contains a metabolically active substance, effectively removes toxins. For treatment, take 200 mg 1 time per day.

• Liposil is a preparation based on milk thistle extract and soy phospholipids. To cleanse the liver, take 1-2 capsules per day.

• Bonjigar - active ingredients: chicory, nightshade, barberry, white eclipta. The product is available in the form of gelatin capsules and syrup. For cleansing, take 1-2 capsules or 15 ml of syrup 3 times a day after meals.

• Allohol - contains condensed bile, activated charcoal, nettle and garlic extract. Enhances the synthesis of bile acids and bile. You can take 1-2 tablets 3-4 times a day.

• Silymarin - this substance is part of many drugs. Favorably affects hepatocytes, accelerates the excretion of bile. For treatment, take 200-300 mg per day.

Magnesium is used to cleanse the liver and gallbladder. This substance increases the acidity of the stomach and has a powerful choleretic effect, so it can be used only with the permission of a doctor. To prepare the medicine, dissolve 2 tablespoons of magnesia in a glass of boiled water and drink the solution 30-40 minutes before meals. Before and after taking the remedy, it is recommended to lie down for 1-2 hours on the right side.

Read the full list of drugs for liver cleansing.

Medicines for the liver after antibiotics

Antibiotics are used to eliminate many diseases. Their long-term use negatively affects the health of all organs and systems. Medicines for the liver after antibiotics restores the filter, since it is he who removes the decay products of drugs, toxins and other harmful substances from the body.

To restore the body, special means are used - herbal remedies, that is, hepatoprotectors. The most popular medicines:

• Medicines with herbal ingredients and milk thistle - Karsil, Liv 52, Galstena, Gepabene, Ovesol. They stabilize cell membranes and have an antioxidant effect.
• Essential phospholipids - Essentiale forte, Essliver, Phosphogliv. Accelerate regeneration processes, have an antifibrotic effect.
• Means with ursodeoxycholic acid - Ursolfak, Ursosan. They protect cell membranes, eliminate the inflammatory process and accelerate the excretion of bile.

For treatment after antibiotics, folk remedies are excellent. But do not forget that such methods are auxiliary therapy, that is, an addition to the main treatment.

• Take milk thistle, corn stigmas and chicory in equal proportions, pour 200 ml of boiling water over them. The broth should be infused for 10-12 hours, after which it must be filtered and taken before meals.
• Pour 2 cups boiling water over chicory flowers and simmer for 20-30 minutes. Strain the medicine, add a couple of slices of lemon and a spoonful of honey, use as tea.
• Finely chop 1 kg of cabbage, add currants or lingonberries, kiwi and orange to it. Toss the salad well and make a dressing of lemon juice, olive oil, spices and apple cider vinegar. Eat salad throughout the week with a piece of black bread.

Medicines for the liver in ampoules

To eliminate diseases of the liver and digestive tract, many drugs are used in different forms of release. Focusing on the results of tests and diagnostics, the course of the disease and the characteristics of the patient's body, the doctor selects the best therapy option.

Medicines for the liver in ampoules:

1. Heptral

Hepatoprotector with antidepressant activity. It has choleretic, cholekinetic, antioxidant, regenerating, neuroprotective effects. The active substance, ademetionine, compensates for its deficiency in the body and takes part in the biological reactions of transmethylation. Increases the content of glutamine in the liver, normalizes metabolic reactions and has a choleretic effect.

• Heptral is prescribed for the treatment of hepatitis of various etiologies, cholecystitis, cholangitis, cholestasis, toxic lesions. Intravenous administration is indicated for fatty degeneration, cirrhosis, encephalopathy, withdrawal syndrome. Ampoules are used intramuscularly or drip intravenously. The daily dosage should not exceed 800 mg.
• It is contraindicated to use in the I-II trimesters of pregnancy and during lactation. Do not prescribe for patients under 18 years of age and with individual intolerance to the components. Side effects appear when the recommended dosage is exceeded. Most often these are allergic reactions and dyspeptic disorders, gastralia.

1. Essentiale N

Solution for intravenous administration from the pharmacological group of hepatoprotectors. The active substance is essential phospholipids 250 mg. The active ingredient regulates the metabolism of lipoproteins and increases their binding to cholesterol. It has a detoxifying, restoring effect, prevents the formation of connective tissue in the liver.

• Used only for intravenous administration, intramuscular injections can cause local allergic reactions. For breeding use 5-10% dextrose solution. The resulting solution should be clear at the time of administration. The use of electrolyte solutions (Ringer's solution, isotonic) for dilution is contraindicated.
• Indications for use: hepatitis, fatty degeneration, cirrhosis, toxic lesions and necrosis of liver cells. It helps with toxicosis during pregnancy, hepatic coma and precoma, with radiation syndrome and psoriasis, in the pre and postoperative period.
• The use of this drug during pregnancy is possible only for medical purposes, since gasoline alcohol penetrates the placental barrier and adversely affects the development of the fetus. It is not used to treat patients under 3 years of age and with hypersensitivity to the components. Side effects are manifested by the immune system, causing allergic reactions and itching.

1. Remaxol

Balanced infusion solution with hepatoprotective properties. Produced in glass bottles of 400 ml. Active ingredients: succinic acid 5.28 g, meglumine 8 g, riboxin 2 g and other components. The drug reduces the content of bilirubin and its fractions, minimizes the activity of excretory enzymes of hepatocytes and oxidizes cholesterol, converting it into bile acids.

• The main indications for use: liver dysfunction in toxic, drug and alcoholic hepatitis. Comprehensive treatment of viral hepatitis. With drip administration, the active components quickly spread through the tissues of the body. The daily dosage is 400-800 ml, the rate of administration is 2-3 ml / min.
• It is contraindicated to use during pregnancy and lactation. Do not prescribe to patients of childhood and with individual intolerance to the components. Under medical supervision, it is used for gout, nephrolithiasis and hyperuricemia. It is not recommended to mix in one vial with other means for intravenous administration.
• In case of an overdose, side effects are possible. With the rapid introduction of the solution, there is a feeling of heat, dryness and sore throat, hyperemia of the skin. Allergic reactions, nausea, headaches, vomiting, dizziness are possible. If these symptoms appear, you should seek medical help to adjust the dose.

1. Laennec

Immunomodulator, available in ampoules for injection. Stimulates humoral immunity, increases the activity of phagocytes, increases the bactericidal activity of leukocytes. Active components stimulate the regeneration of damaged cells, prevent the deposition of cholesterol and lipids.

• Injections are prescribed to eliminate chronic liver diseases of various etiologies. The medication helps with atopic dermatitis and chronic recurrent herpes. In case of liver pathologies, 2 ml per day is prescribed intravenously. The maximum dosage should not exceed 10 ml per day. The course of treatment takes 2-3 weeks.
• It is contraindicated to use for patients of childhood, during pregnancy and lactation. If these recommendations are not followed and the prescribed dosage is exceeded, side effects are possible. Most often, these are painful sensations and numbness at the injection site, allergic reactions.

1. Cryomelt MN

Solution for injection, hepatoprotector. The active ingredient is honey, available in ampoules of 1 ml. The drug is a sterile native solution of honey in water, prepared using a special technology. It has an antioxidant effect and stabilizes the membranes of damaged cells. Hepatoprotective activity provides protection against the negative effects of toxins and harmful substances.

• Cryomelt is prescribed for the treatment of chronic hepatitis and toxic lesions, as well as for fatty degeneration of various etiologies. Patients are administered 1 ampoule per day, the course of treatment is 10-20 days.
• Contraindicated in case of hypersensitivity to bee products and for pediatric patients. It is used with extreme caution by patients with diabetes mellitus. Side effects are manifested as allergic reactions of varying severity.

Liver Medicines for Children

Treatment of any diseases in pediatric patients requires a professional medical approach. Children are prescribed safe drugs with minimal side effects and contraindications.

Consider effective liver medicines for children:

• Galstena is a herbal homeopathic remedy. It has hepatoprotective, anti-inflammatory, choleretic and antispasmodic properties. It is used for the complex therapy of pancreatitis, liver restoration, after prolonged use of antibiotics, with hepatitis and other pathologies. Available in drops, which allows it to be used for the smallest patients.

• Essentiale - the active ingredients of this medication are essential phospholipids. In their structure, they are similar to the endogenous membranes of liver phospholipids. It is prescribed for fatty degeneration, acute and chronic hepatitis, organ cell necrosis and toxic lesions. Available in capsule and injectable form for intravenous administration.

• Allochol is a drug that enhances the formation of bile. It improves the secretory function of the gastrointestinal tract, reduces fermentation processes in the intestines, accelerates the regeneration of damaged liver and gallbladder cells. It is prescribed for the treatment of chronic hepatitis, with cholecystitis, cholangitis, prolonged constipation associated with intestinal atony. Available in the form of enteric-coated capsules.
• Antral is a hepatoprotector, used to treat hepatitis of various etiologies and minimizes signs of dyspeptic and asthenovegetative syndrome. Assign for the treatment of cirrhosis and fatty degeneration, various inflammatory and infectious diseases of the digestive tract. Antral is available in the form of capsules for oral administration.

• Betargin - contains amino acids (betaine, arginine) necessary for the normalization of the functions of the hepatobiliary system. Available in the form of a solution for oral administration. It is used to treat functional disorders of the liver, with hepatosis, viral hepatitis, steatosis, drug and toxic damage to the organ.

Method of application and dosage of drugs for the liver

In order for the treatment to be quick and effective, the doctor prescribes to the patient the method of administration and dose of drugs. For the liver, drugs of different form are used, so the therapeutic effect depends on the method of their use.

• Herbal hepatoprotectors

Gepabene is prescribed 1 tablet 2-3 times a day. If pain in the right hypochondrium appears at night, then an additional capsule is allowed at bedtime. The maximum daily dose is 6 tablets in 3 doses, the duration of therapy is from 3 months.

• Essential phospholipids

The daily dose of Essentiale is 4-6 tablets in 3-4 doses, the duration of treatment is individual for each patient. Tablets are taken without chewing, washed down with water. The dosage of the solution for intravenous injection is up to two ampoules per day.

• Animal products

Hepatosan is taken at 200-400 mg, depending on the indications. The course of treatment is 10-20 days.

• Amino acids

Ursosan is taken at the rate of 10 mg/kg of body weight. The daily dosage is divided into 2-3 doses. For patients under 2 years of age, the dosage is selected individually.

• Biologically active additives

Liv 52 is taken both for therapeutic and prophylactic purposes. For children over 6 years old and adults, 1-3 tablets 2-3 times a day. Drops are used to prevent liver diseases, 10-20 drops 2 times a day for children over 2 years old and 80-160 drops for adults.

Overdose

High doses of the drug may cause adverse symptoms. An overdose manifests itself as an increase in side effects. Most liver medicines are well tolerated. In rare cases, there are signs of disorders of the gastrointestinal tract, headaches.

Interactions with other drugs

The use of several drugs in the elimination of one disease is possible only with the appropriate medical prescription. Interaction with other drugs depends on the form of release of the main drug.

Injections for intravenous and intramuscular administration must not be mixed with other drugs. Since local allergic reactions, redness at the injection site and other symptoms are possible. Particular attention should be paid to solutions for diluting ampoules. In any case, when using several drugs at the same time, it is necessary to observe a time interval of 1-2 hours to prevent side effects.

Best before date

Medicines for the liver help to restore the cells of the damaged organ and improve its functioning. Such medicines are used in the treatment of patients of all ages. In order for the treatment to be safe and effective, before using the drug, it is necessary to study its instructions and pay attention to the expiration date. The use of expired tablets or injections threatens with side effects, disrupts the work of all organs and systems.

Content

Therapy of liver diseases is to eliminate the causes of their occurrence, for example, the neutralization of toxins. However, there is a wide range of drugs, the action of which is aimed at protecting the cells of the body from destruction. What are hepatoprotectors for the liver? This is a special type of remedy that stimulates the recovery process of hepatocytes and protects them from the harmful effects of various toxic substances, fatty, smoked foods, alcohol, chemical compounds and other poisons.

When are hepatoprotectors needed?

Russian pharmacies offer a wide range of drugs for liver cleansing, which are very popular. The cost of a therapeutic course is expensive for patients, although not everyone feels the result. Discussions about the feasibility and necessity of such treatment in medical circles have been going on for a long time, in our country a doctor can prescribe hepatoprotectors in such cases:

• With viral hepatitis. Medicines are prescribed if antiviral drugs do not show the expected effect or antiviral therapy is not possible for any reason.
• With cirrhosis of the liver caused by alcoholism. In this case, the main step towards recovery is the refusal to take alcohol, otherwise hepatoprotectors will be absolutely useless.
• With fatty hepatosis (fatty liver). Hepatoprotectors are used as part of complex therapy, which includes: a low-fat diet, antidiabetic drugs, and regular exercise.
• After chemotherapy. Hepatoprotective agent helps to gradually restore the liver.
• With toxic hepatitis (after taking antibiotics). Hepatoprotectors are effective in combination with other drugs for liver restoration, diet, and the rejection of bad habits.
• Enlarged liver (hepatomegaly). For the rapid regeneration of organ cells and the normal functioning of the organ, hepatoprotectors are used.

Types of hepatoprotectors for the treatment and restoration of the liver

Modern medicine uses the requirements for preparations for cleansing and restoring the organ, which were created back in the 70s of the last century, but the ideal medicine that would suit all patients has never been created. There is a large list of drugs for the liver, including herbal and animal products, dietary supplements, phospholipids, vitamins, synthetic drugs, amino acids. Which hepatoprotectors for liver restoration are suitable for a particular patient and the duration of treatment is determined by the doctor.

Medicines of animal origin

Such funds are made from liver cells of a pig or cattle. Preparations for liver restoration effectively cleanse the gallbladder and biliary tract, have a hepatoprotective effect. They are prescribed for the treatment of cirrhosis, hepatitis, with alcoholic damage to the organ, liver failure. Tablets for the liver of animal origin are released strictly by prescription. These include:

• "Sirepar";
• "Hepatosan";
• "Progepar";
• "Gepadif".

Herbal hepatoprotectors

This group includes preparations based on oils of different seeds, artichoke leaves, extracts of licorice root, senna, chicory, St. John's wort, nightshade, etc. Active ingredients in vegetable hepatoprotectors for the liver may differ. A commonly used drug ingredient is silymarin, which is derived from milk thistle. The substance contains natural flavonoids: silidianin, silibinin, silicristin. Their hepatoprotective properties are due to the ability to accelerate the recovery of liver cells.

Homeopathic medicines include:

• "Geparsil";
• "Holenzim";
• "Hepel";
• "Galstena";
• "Karsil";
• "Silegon";
• "Gepabene";
• "Silimar";
• "Liv-52".

Synthetic drugs

Treatment of the liver with drugs of synthetic origin is considered the most effective for biliary cirrhosis, cholesterol stones, reflux gastritis, organ damage by toxins. Hepatoprotectors based on uvsodeoxycholic acid help with the first stage of sclerosing cholangitis, viral hepatitis with various aggravating factors (childhood, pregnancy, oncological diseases). Synthetic medicine helps to reduce cholesterol, improves pancreatic and gastric secretion, activates the excretion of bile.

List of hepatoprotectors of synthetic nature:

• "Antral";
• "Ursosan";
• "Aeschol";
• "Rezodlut";
• "Cryomelt";
• "Urdoksa";
• "Essliver".

Essential phospholipids

Liver cells have a phospholipid layer. The action of essential phospholipids is aimed at restoring the membrane of hepatocytes by direct incorporation into it. The importance of these components for liver health cannot be overstated. Essential phospholipids are widely used by modern Russian medicine, but rarely used outside the country. They can be prescribed to a child of any age, to women during pregnancy or lactation. Side effects are extremely rare. Among the hepatoprotectors of this group include:

• "Phospholip";
• "Hepaforte";
• "Livolin";
• "Essentiale";
• "Enerliv";
• "Rezalut".

Amino acids

Amino acids are necessary not only for sick people, but also for healthy people - this is the opinion of many doctors. A healthy diet can saturate the body with the necessary amount of these substances, but with a deficiency of amino acids, their intake is mandatory. Amino acid hepatoprotectors are recommended for people with severe liver damage, but they have a less pronounced effect compared to other types of drugs to maintain the hematopoietic organ. Due to ademetionine, (the main active ingredient), which provides for the possibility of negative consequences, amino acids are rarely prescribed.

This group of hepatoprotectors for the liver includes:

• "Heptral";
• "Methionine";
• "Heptor".

vitamins

Previously, the treatment of liver diseases consisted in taking vitamins; there were no other types of hepatoprotectors. In modern pharmacies, there are many vitamin products with different compositions, but not all of them are effective for restoring liver functions. Taking such drugs will not harm even a healthy body, but you should not expect a significant effect in the treatment of the organ. As a rule, the doctor prescribes a vitamin hepatoprotector in combination with other medicines.

Vitamin remedies for the treatment of liver diseases are:

• "Supradin";
• "Complivit";
• "Undevit";
• Vitrum.

Vitamin-like substances

Dietary supplements are rarely used as hepatoprotectors to cleanse and normalize the functioning of the liver, biliary tract, and gall sac, since they do not guarantee the expected therapeutic effect. Despite the doubtfulness of the effectiveness of dietary supplements, some manufacturers have recommended their drugs as effective hepatoprotectors. Among the total mass of bioadditives, it is worth highlighting:

• "Ovesol";
• "Dipana";
• "Hypatrin";
• "Milona-10";
• "Hepatotransit".

List of the best new generation hepatoprotectors

The sheath of the liver has no nerve endings, so a person cannot feel pain until it enlarges so as to put pressure on neighboring organs. Therefore, liver diseases are often discovered by chance, for example, during blood donation or ultrasound examination. Pathological processes are characterized by rapid, irreversible cell death. Hepatoprotectors of a new generation are necessary for the rapid regeneration of hepatocytes, the removal of poisons, and the prevention of tumor development.

The best hepatoprotectors for chemotherapy:

• "Eslidin";
• "Glycyrrhizin";
• "Ursosan";
• "Hepaliv";
• "Liver Pro";
• "Adementionine";
• "Silymarin".

The best liver medicine for hepatitis is:

• "Liv-52";
• "Lohein";
• "Tykveol";
• "Katergen";
• "Bondijar";
• "Eplir".

Hepatoprotectors for children

The liver can work normally only if the membranes of its cells are not damaged. In cases where the membranes are clogged, the body does not cope with its duties, which causes the development of various diseases. Adults are more likely to encounter such problems, but liver diseases do not bypass children. How to treat a child's liver? Therapy of children with hepatoprotectors should be prescribed by a doctor and carried out under his supervision.

• For newborns: Galstena, Hepel.
• Toddlers from 3 years old:

  "Essentiale", "Duphalac".

• Children over 4 years of age:

  "Antral", "Methionine", "Gepabene" and other preparations based on milk thistle.

• From 5 to 12 years:

  Ursosan, Legalon, Karsil.

• Teenagers over 12:

  "Holenzim".

Where to buy and how much

Modern hepatoprotectors for the liver are represented by a large assortment, which often confuses people who come to the pharmacy. Even after carefully studying the characteristics of the drugs, it is difficult to decide which one is better. Only a doctor can choose an inexpensive and effective medicine, who will prescribe the necessary dosage and duration of the course of treatment.

Where are hepatoprotectors sold and how much do they cost in Moscow.

Updated: 05.12.2019

The liver is the largest gland. Takes part in digestion and neutralization of harmful substances. Responsible for the production of bilirubin, cholesterol, enzymes and hormones. Capable of storing blood and glucose. Any violations in the work of the body are manifested by poor health.

Typical signs of failure are bloating, pain, and poor digestion. Harmful food, poor environmental conditions, and an unhealthy lifestyle can harm the liver. If you need treatment or want to take preventive measures, check out the ranking of the best drugs for the liver. You will get the opinion of buyers and experienced professionals. Be sure to consult your doctor before taking.

Essential phospholipids

Pharmaceutical companies offer several medicines containing polyunsaturated (essential) fatty acids. The components have metabolic and hepatoprotective properties. They are used to treat liver diseases.

Designed to restore the structure of the body with hepatitis, fatty degeneration and cirrhosis. Manufacturers also claim that phospholipids have additional properties: they improve metabolism, reduce the likelihood of developing atherosclerosis, improve skin condition, and help after irradiation.

Advantages

• Preparations for liver restoration are well tolerated by patients.
• Reduce the likelihood of disease recurrence.
• Help as a complex drug in the treatment of hepatitis C.
• Easily digestible.
• Assign even during pregnancy.
• Reduce liver costs.
• Improve enzymatic activity and physicochemical parameters of bile.

Flaws

• Pain may occur after intravenous injection.
• They do not restore liver cells, but only cell walls.
• For maximum results, the course of treatment should be at least 6 months.
• It should not be taken concomitantly with preparations containing vitamin B.
• They can activate the inflammatory process.
• High price.

Rating of the best essential phospholipids

Rating

#1

#2

#3

Name

Points

Mild effect on the body

Ease of use

Manufacturer Popularity

Hepatoprotective, antiviral agent with a combined composition. Contains simultaneously two active active components - phospholipids and glycyrrhizic acid.

Has a regenerative effect. Restores the functions and structure of membranes.

It also has cytoprotective properties. Normalizes protein and lipid metabolism.

Produced in capsules for oral use. The best effect is achieved when taking the drug during meals.

It is prescribed for viral hepatitis (both chronic and acute forms), toxic damage and cirrhosis of the liver. As an auxiliary component, it can be used in the treatment of neurodermatitis, intoxication, psoriasis, eczema.

• Prevents loss of enzymes.
• Stimulates the work of the liver.
• Promotes the formation of connective tissue.
• Reduces the risk of cirrhosis and fibrosis.
• Well tolerated by the body.
• Contains herbal ingredients.
• Cheaper than analogues.
• Increases the protective function of the body.
• Eliminates pain in the right hypochondrium.
• Small capsules.

• There are side effects.
• Raises blood pressure.
• duration of treatment.

Dietary supplement helps to fill the body's need for vitamin E and essential phospholipids. Thus, the state of the antioxidant system improves, the functionality of the liver is normalized.

Metabolism is optimized. The drug protects cell membranes from oxidation.

Supports the functioning of the nervous system. Also, "Gepagard" is prescribed for low body resistance to toxins.

To achieve a therapeutic effect, it is necessary to take the drug two capsules with meals. During the day you need to drink dietary supplements 2 times.

The course of treatment is one month.

• Accelerates cell regeneration.
• Improves metabolism.
• Normalizes the work of the digestive tract.
• Improves memory.
• Normalizes the conduction of impulses.
• Safe composition.
• Affordable price.
• Easy to accept.

• A small number of capsules in one package.

One of the most effective hepatoprotectors. Has a combined effect.

Contains essential phospholipids and milk thistle. One capsule of the drug contains seventy milligrams of silimar and one hundred to two hundred milligrams of lipoid.

It also contains additional ingredients. In one package - 30 capsules of a light orange hue.

Normalizes the exchange of proteins, phospholipids and lipids. Helps digest food and activates the production of enzymes.

Stabilizes cell membranes. Protects cells from destruction.

Accelerates the regeneration and excretion of bile. Prevents the formation of connective tissue.

• Removes toxins from the body.
• Has antioxidant properties.
• There are practically no contraindications and side effects.
• Protects tissues from toxic damage.
• Restores the structure and functions of the liver.

• During the day you need to take about 6 capsules.
• The high cost of the drug.

The drug was created to prevent acute liver diseases. It also stops the progression of existing chronic ailments.

Helps to lead a full-fledged lifestyle in chronic hepatitis and cirrhosis. Regulates carbohydrate and fat balance.

Has a detoxifying effect. Like other hepatoprotectors, it is prescribed in combination to eliminate organ damage.

Contains fat metabolism products and B vitamins, including pyridoxine hydrochloride, riboflavin, cyanocobalamin, thiamine mononitrate. Helps the body cope with heavy foods - broths, mayonnaise, fatty and fried foods, cakes with cream and alcohol.

• Helps to remove toxins and slags.
• Affordable price compared to foreign counterparts.
• Improves blood counts. Proven by ALT test results.
• Supports the body during a diet.
• Can be taken by children.
• Helps within a few days after the first application.

• Fragile capsules.
• Not produced in ampoules.
• There are contraindications.
• May cause side effects.
• To consolidate the result, you need to take several months.

The drugs are designed for the prevention and treatment of the liver. Can change the cellular structure of an organ.

Improve the density of membranes and restore their functionality. Able to relieve severe symptoms of the disease in a short time, improve well-being.

The composition includes linoleic and linolenic acid. One pack contains 30 capsules.

Each of which contains 6 milligrams of thiamine, 3 thousand milligrams of essential phospholipids and 6 milligrams of riboflavin.

In addition to these active substances, there are also auxiliary components. .

• Contains no vitamins. The therapeutic effect is provided by hepatoprotectors.
• Unlike classic multivitamin complexes, the drug can be taken without harm to health for a long time.
• Has a detoxifying effect.
• Stops cirrhosis of the liver.
• Safe composition.
• Slows down the inflammatory process and reduces the degree of tissue necrosis.
• Improves the general condition of the digestive tract and well-being in general.
• Released without a prescription.
• You can buy at any pharmacy.
• Suitable for treatment during pregnancy.

• For a stable and long-term effect, you need to take the drug from 3 to 12 months.
• Not prescribed for children.
• Contraindicated in case of individual intolerance to phosphatidylcholine.

Preparations for the liver of plant origin

According to experts, the best herbal medicines contain milk thistle. These include Karsil, Legalon, Silimar, Gepabene, Sibektan. The main active ingredient of such drugs is silymarin. It combines three compounds - silidianin, silicristin and silibinin.

It has antioxidant and membrane stabilizing properties. Counteracts liver stress (oxidative). It has an immunomodulatory effect. Protects the body from alcohol disease. With prolonged use - about six months, the number of cytotoxic lymphocytes and the production of gamma globulin decreases. Minimizes the susceptibility of cells to toxic substances.

Advantages

• Natural composition.
• Promote cell regeneration.
• Stimulates protein synthesis.
• They have a choleretic effect.
• Increase the secretion of bile acids.
• Eliminate spasm of the biliary tract.
• Can be used for prevention.
• They have a strong antioxidant effect.

Flaws

• Manufacturers, in addition to milk thistle, may use other, less safe ingredients.
• The course of treatment, as a rule, is at least 3 months.
• The effectiveness of drugs during the treatment of acute hepatitis or alcohol abuse has not been clinically proven.

Rating of the best drugs for the liver of plant origin

Rating

#1

#2

#3

Name

Points

Mild effect on the body

Ease of use

Improvement of the digestive tract

Manufacturer Popularity

Effective pain relief

The composition of the drug includes extracts of St. John's wort, common tansy and milk thistle. Helps in the treatment of alcoholic fatty liver disease, alcoholic liver disease, alcoholic cirrhosis of the liver, chronic cholecystitis and chronic persistent hepatitis.

It has hepatoprotective, membrane-stabilizing, antioxidant and choleretic effects. Has a mild effect.

Doctors also prescribe the drug in combination with others to restore liver cell membranes and have a better antioxidant effect. "Sibektan" also additionally has a tonic property.

Relieves depression, improves the functioning of the digestive tract. Clinically proven anti-inflammatory and antibacterial properties.

For maximum effectiveness, take on an empty stomach half an hour before a meal. The daily dose should not exceed 800 milligrams.

The standard course of treatment is 20 weeks. According to the doctor's decision, it will need to be repeated after 2 or 3 weeks.

• It has a complex effect. May help with peptic ulcer, gastritis or kidney disease.
• Does not cause overdose.
• Safe composition.
• Various release forms.

• During the day you need to take a lot of pills. You have to get used to the new regime.
• There are contraindications.
• Not prescribed for under 18s.

The drug contains herbal ingredients. It has antitoxic and hepatoprotective properties.

Designed for the treatment of cirrhosis of the liver, toxic damage to the organ, as well as for recovery from hepatitis. Assign as a prophylaxis for intoxication in a chronic form.

With prolonged use of medications and alcohol abuse. The medicine should be taken before meals, half an hour.

The standard dosage includes one or two liver repair tablets three times a day. The course of therapy, depending on the severity of the disease, is 25-30 days.

To prevent a recurrence of a chronic disease, a repeated course of treatment with an interval of one to three months will be required.

• Contains ingredients of plant origin.
• It has antitoxic and hepatoprotective effects.
• Slows down the penetration of toxins into cells.
• Stimulates regeneration.
• Fast effective action.
• Affordable price.
• Relieves pain.
• Can be used in combination with other drugs.

Complex preparation with plant components. Contains an extract of fumes, fruits of milk thistle.

Has a choleretic effect. It also normalizes the amount of its production and reduces the tone of the sphincter.

It has a hepatoprotective effect. Protects liver cells from alcohol and toxins.

Stimulates hepatocyte recovery and protein synthesis. Suitable for the treatment of liver diseases at various stages - acute and chronic.

For maximum effect, take after meals. The standard dosage for adults is one capsule three times a day.

To relieve severe pain, the doctor may prescribe an additional dose before bedtime. The product is produced in hard capsules.

The package contains thirty pieces.

• Natural composition.
• Fast effect.
• Removes severe pain.
• Improves the functioning of the digestive tract.
• Removes heaviness.
• Affordable price.
• After application, constant nausea disappears.

• You can not take with individual intolerance to one of the active ingredients.
• Do not prescribe for acute inflammatory processes of the liver and biliary tract.
• Caution should be taken during pregnancy and breastfeeding.
• Inconvenient release form - large capsules.
• Laxative effect.

Refers to herbal medicines. Assign for diseases of the gastrointestinal tract and severe pathological conditions of the liver.

The composition includes flavonoid isomeric compounds. Produced in the form of dragees, capsules and suspensions.

The main active ingredient is isolated from milk thistle. The drug has a hepatoprotective and antitoxic effect.

Normalizes physical and chemical indicators. Slows down the penetration of toxic components into the liver cells.

Accelerates the regeneration of body cells. It is prescribed for lesions with several medicines - Paracetamol, antidepressants, antibiotics, after anesthesia, immunosuppressants and psychotropics.

• Relieves skin itching, vomiting.
• Eliminates heaviness in the right hypochondrium.
• Restores appetite.
• Improves general condition.
• According to the results of the analyzes, bilirubin, transaminases, and alkaline phosphatase activity decrease.
• Contains natural ingredients.

• High price.
• May cause diarrhea.
• Contains dyes.

The drugs belong to hepatoprotectors from the group - herbal preparations. Silymarin is used as the main active ingredient.

It is obtained from milk thistle fruit. Produced by the Bulgarian company Sopharma.

The drug with the prefix "forte" has a high concentration of the active ingredient. They produce a classic drug in the form of a brown dragee.

In one package - 80 pieces. Carsil Forte contains 30 capsules of gelatin structure.

Has a specific smell. It is prescribed for toxic liver damage as a result of long-term treatment, for chronic and alcoholic intoxications, cirrhosis, steatosis, for recovery from acute hepatitis.

• Has a stabilizing effect.
• Normalizes fat metabolism.
• Stimulates the production of phospholipids.
• Protects liver cells from the negative effects of toxins.
• Restores hepatocytes.
• It slows down the fatty degeneration of the organ and the development of fibrosis.
• Has an antioxidant effect.
• Normalizes blood microcirculation.
• Improves general condition, including increases appetite.

Liver tablets - bile acids

Ursodeoxycholic acid (UDCA) is the only acid of its kind that does not harm the human body. Refers to the means of bile acids. Assign for the treatment of diseases of the liver and biliary tract, cholelithiasis (not complicated type).

It should not be taken with an increased calcium content of gallstones. It has hypoglycemic properties. Increases gastric and pancreatic secretion. Can change the immune response of the liver. You can not take the drug without a doctor's prescription. There are very serious contraindications.

Advantages

• Reduces the number of eosinophils.
• In combination with other drugs, it will help dissolve cholesterol formations in the gallbladder.
• It will help with toxic, alcoholic liver damage.
• Can be used by pregnant women to treat hepatopathy.
• One of the most effective means for the treatment of sclerosing cholangitis (primary type) and biliary cirrhosis.
• Assign the most vulnerable category of patients - in adolescence, pregnancy. And also for the treatment of hemophilia, substance abuse and drug addiction.

Flaws

• There are many drugs with unconfirmed quality.
• They can harm with inflammation of the gallbladder, intestines, disruption of the kidneys, pancreas, liver.
• Often there is an individual intolerance.

Rating of the best bile acid drugs for the treatment of the liver

Rating

#1

#2

#3

Name

Points

Mild effect on the body

Ease of use

Improvement of the digestive tract

Manufacturer Popularity

Effective pain relief

Hepatoprotector with choleretic, choleretic, hypocholesterolemic, and immunomodulatory effects. Increases the protection of liver cells from bile acids.

Changes their structure. Improves the production and excretion of bile.

Destroys gallstones and protects the liver from the harmful effects of alcohol. Ursodeoxycholic acid in the composition of the drug prevents cholestatic liver disease.

Produced in the form of gelatin capsules of a milky shade. The number of capsules, as well as the duration of administration, depends on the disease and body weight.

It is prescribed for biliary cirrhosis at the stage of compensation of the primary type, with biliary reflux gastritis, medium and small cholesterol stones. Intended for oral use.

• Reduces the production of cholesterol.
• Minimizes the lithogenicity of bile.
• Breaks down cholesterol stones.
• Replaces toxic bile acids with non-toxic ones.
• Improves the secretion of liver cells.
• Improves immunoregulatory processes in the body.
• Copes with stagnant bile.

• The drug is not prescribed to children.
• For long-term use, significant costs will be required.
• Causes side effects - nausea, vomiting, constipation, diarrhea.

An effective hepatoprotective drug with a choleretic effect. Reduces the concentration of cholesterol in the blood, its further absorption in the intestine.

Promotes the formation and secretion of bile. Enhances pancreatic and gastric secretion.

It has hypoglycemic properties. When administered enterally, it partially or completely dissolves cholesterol stones.

Promotes the removal of organic compounds from gallstones. It has an immunomodulatory effect.

The main active ingredient is ursodeoxycholic acid. Dosage and duration of treatment depends on the disease.

To dissolve gallstones, you will need to take Ursodez at the rate of ten milligrams of the active ingredient per kilogram of body weight. The best time to use is before bed.

Capsules should not be chewed. It is important to drink a small amount of water.

• It can be taken for a long time - up to 24 months.
• It is very easy to evaluate the effectiveness of the drug using ultrasound diagnostics or radiography.
• Effective treatment.
• It has a complex effect.
• Convenient release form.
• Small capsule size.
• The minimum number of side effects.

The hepatoprotector is produced in the form of white gelatin capsules. Packaged in plastic bottles or blisters.

It has a choleretic effect. Does not allow the formation of stones.

Displays existing gems. Effectively affects the composition of bile, the work of the pancreas and stomach.

Activates the functions of liver cells. Increases the protective functions of the body.

Absorbed in the small intestine. The maximum concentration is observed in the blood two hours after ingestion.

It then binds to plasma proteins. As a result of prolonged intake, it turns into a basic bile acid.

It is located in the blood serum.

• Decreased secretion of cholesterol.
• Toxins are removed from the body faster.
• Improves the work of the pancreas and stomach.
• Increased lipase activity.
• The level of sugar in the blood drops.
• Convenient packaging.
• Works effectively. The dynamics can be tracked by the results of the analyzes.
• Affordable price.

• It is forbidden to take the drug with calcified stones, obstruction of the bile ducts, acute inflammatory processes, hepatic colic, with a weight of less than 34 kg.
• Causes nausea, vomiting, pain, diarrhea or constipation.
• Can calcify gallstones.
• Exacerbates psoriasis.
• Leads to hair loss from the scalp.

Contains ursodeoxycholic acid. Assign in the treatment of diseases of the digestive tract.

The main active ingredient reduces the synthesis of cholesterol. Due to this, an increase in the concentration in the intestine occurs.

The drug has a particularly effective effect when the disease is not running. Doctors recommend taking the medicine in the evening.

It is enough to drink the capsules with plenty of water. In the first days of admission, you need to control the level of liver enzymes.

• The drug replaces harmful bile acids (with toxins) with non-toxic UDCA.
• Stimulates the protective functions of the body.
• Improves the secretory properties of liver cells.
• "Ursosan" is quickly broken down and excreted from the body.
• Painlessly dissolves stones.
• Relieves gastritis.
• Wide spectrum of action.
• Safe composition.
• Eliminates colic in the right hypochondrium.
• Reduces cholesterol levels.
• Helps with jaundice in newborns.

• Do not prescribe if the diameter of the stones exceeds 15 mm.
• May not help with biliary cirrhosis of the primary type, even with prolonged use - from 6 to 24 months.
• There are contraindications. You can not take with inflammation of the gallbladder and gallstones in acute form, colic, and obstruction.
• Causes side effects.
• Be wary appoint with hepatitis and cirrhosis of the liver.
• As a standard, the drug is allowed to be given to children from 5 years of age. But the age threshold can be changed at the discretion of the doctor.
• Exceeding the dosage indicated in the instructions causes a disorder. You need to stop the drug and consult a doctor. It is necessary to restore the water-salt balance in the body.

Has a choleretic effect. Breaks down cholesterol stones.

Prevents the growth of connective tissue after damage to liver cells. Contains ursodeoxycholic acid.

The substance forms micelles of a mixed type. Protects membranes from damage.

Increases the content of bile acids. Which, in turn, contributes to the dissolution of cholesterol gallstones.

Enhances the secretion of the pancreas and stomach. It also has an immunological effect.

Regulates the number of immune cells. Suspends fibrosis in primary biliary cirrhosis, cystic fibrosis, and alcoholic liver disease.

Reduces the likelihood of varicose veins in the esophagus. As a result of research, the effectiveness of "Ursofalk" in delaying the development of tumor tissues has been proven.

Therefore, it is prescribed in combination with other drugs for the treatment of colon cancer. Produced in the form of a suspension and capsules.

• There are no age restrictions.
• Reduces bilirubin. They are prescribed even for newborns.
• Can be used in combination with other drugs and herbal decoctions.
• Dissolves gallstones.
• Eliminates the bend of the gallbladder.
• Has a choleretic effect.
• Eliminates allergic reaction.
• Can be used during pregnancy. Prescribed for hypatosis.
• Relieves nausea and itching.

Tablets for the liver of animal origin

There are only a few such drugs. They are usually not prescribed as a prophylaxis. Suitable for the treatment of liver diseases for several reasons - hepatitis, cirrhosis, fatty liver, toxic and drug-induced hepatitis. Depending on the preparation, porcine liver cells, hydrolysed bovine liver, cyanocobalamin, amino acids, segments of liver growth factors and low molecular weight metabolites are used for production. Pharmaceutical companies also produce drugs with a combined effect.

Advantages

• Able to restore the structure of cells.
• Improve blood flow.
• Change the functional indicators of the liver.
• After taking, as a rule, diuresis increases.
• Can be used in combination with other drugs for the treatment of cirrhosis, chronic hepatitis, radiation sickness, fatty degeneration, drug intoxication.

Flaws

• There is no official confirmation of the clinical safety and efficacy of drugs.
• With extreme caution, you need to take the medicine in the acute stage of hepatitis. There is a possibility of aggravation of the inflammatory, immunopathological, cytological syndrome.
• Causes a severe allergic reaction. Before starting treatment, you need to check for hypersensitivity to the components of the drug.
• Bovine liver hydrolysates can cause prion infection. The latter, in turn, causes Creutzfeldt-Jakob disease (a dangerous neurodegenerative disease).
• It is not recommended to take as a preventive measure.

The drug is prescribed in capsules or suspension (for children weighing up to 34 kg). The dosage is determined at the rate of 10 mg / 1 kg of weight. The duration of recovery with this tool is 6-12 months.

Ursosan

The dosage is selected individually depending on the diagnosis, the characteristics of the body. It is calculated in the ratio of 10 mg / 1 kg of weight.

Ursosan can be used to treat and restore liver cells in pregnant women, lactating women, but only with the permission of a doctor. Also, the drug is allowed to be given to newborn children who have observed.

Livodex

The main active ingredient is ursodeoxycholic acid. Recommended for diseases of the gastrointestinal tract of chronic, subacute and acute types. The average daily dosage is 10 mg/kg. The general treatment course of liver diseases can reach up to a year. It is prescribed even at the age of 3 years, pregnant, lactating.

Other

There are also a number of bile acid medications that can help with a variety of liver problems. Used to restore it:

• Ursodez;
• Ursodex;
• Urdox;
• Grinterol;
• Choludexan.

Amino acid derivatives

These are important components for the "building" of proteins and other components of a healthy liver.

Heptral

This is an Italian drug containing ademetionine. It has a complex effect on the liver, it is often recommended for cirrhosis or, as well as for recovery from alcohol and drug addictions. Heptral injections are more effective. The daily dose of oral medication is 850-1600 mg. When administered by injection, the dosage is 400-800 mg.

The drug often gives side effects, therefore it is prohibited until the age of majority, for women during pregnancy.

hepa-merz

This is an original medicine based on the ornithine-aspartate compound. It should be used to treat chronic liver pathologies, as a result of which the level of ammonia in the body increases.

Before choosing any hepatoprotector - consult your doctor. There are contraindications.

Hepa-Merz is available in tablet form and granules. Depending on the neglect of the disease, up to 8 ampoules are drunk per day. Granules are taken orally 1-2 sachets three times a day after meals. The general treatment course is 3-4 weeks.

Betargin

This is a drug with the amino acids arginine and betaine. Betargin, which has a mild effect, is taken in 2-3 containers during the day. The contents of the container or sachet are preliminarily diluted with water in an amount of 100 ml. The general treatment course is 3-6 months.

Heptor

Another drug in this group is Heptor - tablets with the amino acid ademetionine. It is used in the same way as Heptral. Has side effects, contraindications. Before use, a doctor's consultation is required.

Other medicines

The doctor may prescribe other drugs to restore liver function.

Nucleks

It is an antiviral drug with ribonucleic acid. The main indication for the use of the drug is viral hepatitis. It is prescribed orally at 500 mg three times a day for 5-7 days, and then at 250 mg 2 times for 7-14 days.

Potassium orotate

This is a non-hormonal anabolic agent with a stimulating and restorative effect on metabolic processes. The dosage is as follows: 250-500 mg 4 hours after a meal in a course of 20-40 days.

Methyluracil and Pentoxyl

Substances stimulate the growth and restoration of the cellular tissue of the liver, due to which the organ heals. Methyluracil is used in doses of 0.5 g during meals for 10-15 days. Pentoxyl is drunk in tablet form of 0.2 g for 2-3 weeks.

Riboxin

A remedy with a powerful active substance - inosine, recommended for hepatitis, cirrhosis of the liver,. The course for a full recovery of health is set individually.

Alpha Lipoic Acid

It is used for diabetic polyneuropathy, which accompanies liver disorders. A single dosage of the tablet form is 600 mg. With drip application, the dose is 300-600 mg / day.

Vitamin complexes

A complete therapy cannot be imagined without vitamins and minerals:

• Liver active Nutrilite - to stimulate metabolic processes. Taken in a capsule twice a day.
• Liver Optimizer - A diverse formulation designed to restore and detoxify the liver. The recommended dose is 1 capsule per day.
• Heparosis forte is a complex drug for restoring the working capacity of the liver after poisoning and diseases. The daily amount of vitamins is contained in one capsule.
• Hepaton-2. Improves metabolism, provides detoxification cleaning, stimulates the secretory function of the liver.

Homeopathy

Homeopathic medicines work slowly but gently. They are used for alcoholic and other hepatoses, cirrhosis, hepatitis in order to restore the functionality of not only the liver, but also other organs.

Here is a list of homeopathic medicines:

• Holeton Edas-113. This is a solution for the restoration of internal organs from extracts of celandine and dandelion. 1-6 drops should be diluted with boiled water, taken half an hour before meals three times a day.
• Hepel. The remedy should be sucked on a tablet on an empty stomach after waking up, then an hour after lunch, dinner.
• Enterix - a remedy for restoring health based on camphor, echinacea, chamomile. Accepted by 6-8 pcs. per day.
• Galstena with milk thistle, dandelion, celandine. 10-15 drops or capsule four times for the first 2 days, then twice.
• Leptandra compositum is a liquid remedy for restoring and stimulating liver activity. Drink 10 drops 2-5 times an hour after a meal.

Other medicines

There are also natural preparations for the liver -. They strengthen, cleanse, regulate the balance of nutrients, minimize the risk of complications. They do not remove the cause of pathologies, but eliminate unpleasant symptoms.

• Ovesol with extracts, turmeric, mint, immortelle. Accepted by 1 pc. or 15-20 drops during meals twice a day.
• Hepatotransit is a drug for the restoration of hepatocytes from agrimony, oats, corn stigmas. Directions for use: 5 ml per glass of water, 4 glasses per day.
• Milona 10 with an extract from the roots of burdock, elecampane, dandelion, corn stigmas, artichoke. The dosage is 2 pcs. 2-3 times a day.

How to improve the effectiveness of treatment

To be effective, it is important to observe while taking medication: eat more fiber, exclude spicy, fatty foods, fast food, alcohol. People who are obese should see a nutritionist who will prescribe remedies to restore normal weight.

Precautions and contraindications

Many medicines are prohibited during pregnancy and lactation. If during this period problems with the liver began, it is urgent to contact the doctors, who, after the examination, will prescribe the necessary drug.

All medicines have contraindications and side effects. To avoid them, you must carefully read the instructions for use, follow the dosage, do not try to be treated on your own.

Literature

• Cherenkov, V. G. Clinical oncology: textbook. allowance for the postgraduate system. education of doctors / V. G. Cherenkov. – Ed. 3rd, rev. and additional - M.: MK, 2010. - 434 p.: ill., tab.
• Ilchenko A.A. Diseases of the gallbladder and biliary tract: A guide for physicians. - 2nd ed., revised. and additional - M .: LLC "Publishing House" Medical Information Agency ", 2011. - 880 p.: ill.
• Tukhtaeva N. S. Biochemistry of biliary sludge: Dissertation for the degree of candidate of medical sciences / Institute of Gastroenterology of the Academy of Sciences of the Republic of Tajikistan. Dushanbe, 2005
• Litovsky, I. A. Cholelithiasis, cholecystitis and some associated diseases (issues of pathogenesis, diagnosis, treatment) / I. A. Litovsky, A. V. Gordienko. - St. Petersburg: SpetsLit, 2019. - 358 p.
• Dietology / Ed. A. Yu. Baranovsky - Ed. 5th - St. Petersburg: Peter, 2017. - 1104 p.: ill. - (Series "Doctor's Companion")
• Podymova, S.D. Liver Diseases: A Guide for Physicians / S.D. Podymov. - Ed. 5th, revised. and additional - Moscow: Medical Information Agency LLC, 2018. - 984 p.: ill.
• Schiff, Eugene R. Introduction to Hepatology / Eugene R. Schiff, Michael F. Sorrel, Willis S. Maddray; per. from English. ed. V. T. Ivashkina, A. O. Bueverova, M.V. Maevskaya. - M.: GEOTAR-Media, 2011. - 704 p. - (Series "Liver diseases according to Schiff").
• Radchenko, V.G. Fundamentals of clinical hepatology. Diseases of the liver and biliary system. - St. Petersburg: Dialect Publishing House; M .: "Publishing house BINOM", - 2005. - 864 p.: ill.
• Gastroenterology: Handbook / Ed. A.Yu. Baranovsky. - St. Petersburg: Peter, 2011. - 512 p.: ill. - (Series "National Medical Library").
• Lutai, A.V. Diagnosis, differential diagnosis and treatment of diseases of the digestive system: Textbook / A.V. Lutai, I.E. Mishina, A.A. Gudukhin, L.Ya. Kornilov, S.L. Arkhipova, R.B. Orlov, O.N. Aleutian. - Ivanovo, 2008. - 156 p.
• Akhmedov, V.A. Practical Gastroenterology: A Guide for Physicians. - Moscow: LLC "Medical Information Agency", 2011. - 416 p.
• Internal diseases: gastroenterology: Textbook for classroom work of 6th year students in the specialty 060101 - general medicine / compiled by: Nikolaeva L.V., Khendogina V.T., Putintseva I.V. – Krasnoyarsk: type. KrasGMU, 2010. - 175 p.
• Radiology (radiation diagnostics and radiation therapy). Ed. M.N. Tkachenko. - K .: Book-plus, 2013. - 744 p.
• Illarionov, V.E., Simonenko, V.B. Modern methods of physiotherapy: A guide for general practitioners (family doctors). - M .: OJSC "Publishing House" Medicine "", 2007. - 176 p.: ill.
• Schiff, Eugene R. Alcoholic, drug, genetic and metabolic diseases / Eugene R. Schiff, Michael F. Sorrel, Willis S. Maddray: trans. from English. ed. N. A. Mukhina, D.T. Abdurakhmanova, E.Z. Burnevich, T.N. Lopatkina, E.L. Tanashchuk. - M.: GEOTAR-Media, 2011. - 480 p. - (Series "Liver diseases according to Schiff").
• Schiff, Eugene R. Cirrhosis of the liver and its complications. Liver transplantation / Eugene R. Schiff, Michael F. Sorrel, Willis S. Maddrey: trans. from English. ed. V.T. Ivashkina, S.V. Gotye, Ya.G. Moisyuk, M.V. Maevskaya. – M.: GEOTAR-Media, 201st. – 592 p. - (Series "Liver diseases according to Schiff").
• Pathological physiology: Textbook for medical students. universities / N.N. Zaiko, Yu.V. Byts, A.V. Ataman and others; Ed. N.N. Zaiko and Yu.V. Bytsya. - 3rd ed., revised. and additional - K .: "Logos", 1996. - 644 p.; ill.128.
• Frolov V.A., Drozdova G.A., Kazanskaya T.A., Bilibin D.P. Demurov E.A. pathological physiology. - M .: JSC "Publishing House" Economics ", 1999. - 616 p.
• Mikhailov, V.V. Fundamentals of Pathological Physiology: A Guide for Physicians. - M.: Medicine, 2001. - 704 p.
• Internal Medicine: Textbook in 3 volumes - Vol. 1 / E.N. Amosova, O. Ya. Babak, V.N. Zaitsev and others; Ed. prof. E.N. Amosova. - K .: Medicine, 2008. - 1064 p. + 10 s. col. incl.
• Gaivoronsky, I.V., Nichiporuk, G.I. Functional anatomy of the digestive system (structure, blood supply, innervation, lymph drainage). Tutorial. - St. Petersburg: Elbi-SPb, 2008. - 76 p.
• Surgical diseases: Textbook. / Ed. M. I. Kuzina. – M.: GEOTAR-Media, 2018. – 992 p.
• Surgical diseases. Guidelines for the examination of the patient: Textbook / Chernousov A.F. etc. - M.: Practical medicine, 2016. - 288 p.
• Alexander J.F., Lischner M.N., Galambos J.T. Natural history of alcoholic hepatitis. 2. The long term prognosis // Amer. J. Gastroenterol. - 1971. - Vol. 56. – P. 515-525
• Deryabina N.V., Ailamazyan E.K., Voinov V.A. Cholestatic hepatosis of pregnant women: pathogenesis, clinic, treatment // Zh. and wives. disease. 2003. No. 1.
• Pazzi P., Scagliarini R., Sighinolfi D. et al. Nonsteroidal antiinflammatory drug use and gallstone disease prevalence: a case-control study // Amer. J. Gastroenterol. - 1998. - Vol. 93. – P. 1420–1424.
• Marakhovsky Yu.Kh. Gallstone disease: on the way to the diagnosis of early stages // Ros. magazine gastroenterol., hepatol., coloproctol. - 1994. - T. IV, No. 4. - P. 6–25.
• Higashijima H., Ichimiya H., Nakano T. et al. Deconjugation of bilirubin accelerates coprecipitation of cholesterol, fatty acids, and mucin in human bile–in vitro study // J. Gastroenterol. - 1996. - Vol. 31. – P. 828–835
• Sherlock S., Dooley J. Diseases of the liver and biliary tract: Per. from English. / Ed. Z.G. Aprosina, N.A. Mukhin. - M.: GEOTAR Medicine, 1999. - 860 p.
• Dadvani S.A., Vetshev P.S., Shulutko A.M., Prudkov M.I. Cholelithiasis. – M.: Ed. house "Vidar-M", 2000. - 150 p.
• Yakovenko E.P., Grigoriev P.Ya. Chronic liver diseases: diagnosis and treatment // Rus. honey. zhur. - 2003. - T. 11. - No. 5. - P. 291.
• Sadov, Alexey Cleansing the liver and kidneys. Modern and traditional methods. - St. Petersburg: Peter, 2012. - 160 p.: ill.
• Nikitin I.G., Kuznetsov S.L., Storozhakov G.I., Petrenko N.V. Long-term results of interferon therapy for acute HCV hepatitis. // Ross. magazine gastroenterology, hepatology, coloproctology. - 1999, vol. IX, No. 1. - p. 50-53.

Content

The liver is a unique organ that performs a protective function, cleanses the blood of toxins, toxins and other chemical elements that are harmful to the human body. At the same time, it is capable of self-healing, but sometimes, for various reasons, its own protective potential is not enough for it. Then modern pharmacology suggests using hepatoprotectors. Take these medicines according to the instructions and only on the advice of a doctor.

What are Liver Recovery Pills

Hepatoprotectors are an extensive class of medications that have a stimulating effect on liver cells, help restore its structure and functionality. These drugs are available in the form of tablets, pills or dragees. They help maintain the integrity of hepatocytes, improve the excretion of harmful substances, improve the outflow of bile and restore the absorption of vitamins by the body.

Groups

There are a lot of different hepatoprotectors today. Each of these drugs is generally responsible for one function - restoring the organ's performance and minimizing the damage caused to it, but in fact they can differ somewhat from each other. According to the active active substance, all preparations for liver restoration can conditionally be divided into several classes:

• Phospholipids are substances obtained by special processing of soybeans. Their action is to improve the state of cell walls at the lipid level, increase enzymatic activity, and increase the likelihood of a response to α-interferon. Phospholipid-based liver recovery pills include: Essentiale N, Essentiale Forte N, Essliver Forte, Phosfonciale, Gepagard, Phosphogliv, Rezalyut.
• Derivatives of amino acids. The active components of the preparations are involved in the production of phospholipids and the processes of assimilation of biologically active substances, reduce the level of ammonia, start the processes of self-healing of gland cells and purification. Medications with amino acids: Hepa-Merz (Ornithine aspartate), Heptral, Heptor.
• Medicines of animal origin. The composition includes hydrolyzed pork liver. Known medicines: Sirepar, Progepar, Hepatosan.
• Medicines with the addition of medicinal plants. They are used for organ damage by toxins, poisons or medicines, for cholecystitis, hepatitis, cholelithiasis and for preventive purposes. These include products based on milk thistle (Legalon, Karsil, Gepabene, Silimar), artichoke (Tsinariks, Hofitol), pumpkin seed oil (Tykveol, Peponen), elecampane or burdock root, volodushka herb, agrimony, corn stigmas.
• Homeopathic remedies. Drugs help eliminate numerous symptoms, improve the functionality of the organ, and are used to cleanse it. Best pills: Hepel, Galstena, May celandine and milk thistle.
• dietary supplements. Biologically active food supplements help to better absorb vitamins, cleanse the liver, and restore its structure. Popular supplements: Hepatamine, Hepatotransit, Artichoke extract, Hepatotransit, Milona 10, Ovesol, Dipana, Hepatrin.
• Bile acids. Medicines have a hypoglycemic and choleretic effect, lower cholesterol levels, increase the secretion of gastric juice, and affect immunological reactions. Popular tablets: Ursosan, Urdox, Livodex, Ursodez, Ursofalk, Ursoliv.

Indications for use

It is possible to be treated with hepatoprotectors only after consulting a doctor. They are prescribed for the following diagnoses:

• Alcoholic hepatitis, which increases the risk of developing cirrhosis. To achieve success with drug treatment, it is necessary that the patient completely refuses to drink alcohol.
• Fatty hepatitis - provided that it is not a consequence of alcoholism - the growth of fat cells. Often people with type 2 diabetes or obesity suffer from this disease.
• Hepatitis of viral etiology - primary treatment is carried out with antiviral drugs. Hepatoprotectors are prescribed only when the first course of therapy has not brought the desired result.
• Toxic hepatitis or primary biliary cirrhosis - hepatoprotectors are prescribed as the basis for the complex treatment of the disease and subject to diet.

Hepatoprotectors for the liver

In addition to restoring the cell walls of the organ, good hepatoprotectors should regulate intracellular metabolism, stimulate the outflow of bile, remove toxins and toxins, prevent further spread of infection, and stop the inflammatory process. To achieve good results, you must follow a diet, give up bad habits, and lead an active lifestyle. The following medicines have proven themselves well: Heptral, Essentiale, Liv 52, Osalmid and some others.

FanDetox

A biologically active supplement for the restoration of the liver gland is produced by the Korean company Coral Club in the form of a powder in individual foil bags weighing 4.5 grams each. The product contains only natural ingredients:

• glucose;
• persimmon fruit extract;
• extract of Chinese wolfberry;
• soy sprouts;
• Japanese mandarin peel extract;
• buckwheat seeds;
• taurine;
• citric acid;
• stevia glycoside;
• ascorbic acid.

FanDetox is prescribed to protect the body from the pathological effects of alcohol, drugs, and poor-quality food on it. Before taking the contents of the sachet must be dissolved with half a glass of warm water. The drink is drunk 2 times a day after meals for a month. No side effects were recorded during the treatment, but FanDetox is categorically contraindicated:

• during lactation;
• patients with bowel disorders;
• during pregnancy;
• with individual intolerance to the components;
• with disorders of carbohydrate metabolism.

Tablets for the restoration of hepatic function are available in cardboard boxes of 20 pieces. The drug has hepatoprotective, detoxifying, neuroprotective properties, pronounced antidepressant activity, activates the regenerating functions of the hepatic gland. Heptral contains:

• ademetionine (the main active ingredient);
• talc;
• magnesium stearate;
• polysorbate;
• silica;
• sodium glycolate;
• simethicone;
• purified water.

Heptral is prescribed by physicians after the diagnosis and the following diagnoses:

• intrahepatic cholestasis against the background of fatty degradation, alcoholic hepatosis, viral or drug-induced hepatitis, toxic or drug-induced liver damage;
• chronic hepatitis of various origins;
• fibrosis;
• cirrhosis;
• severe intoxication with drugs, alcohol, food;
• depression.

Heptral must be taken in the morning. The daily dosage is 800-1600 mg, the course of treatment is determined individually. The drug should be abandoned for genetic metabolic disorders, patients under 18 years of age, people with bipolar disorder. While taking Heptral, undesirable effects may occur:

• within the nervous system - dizziness, migraine, paresthesia, insomnia. confusion;
• cardiovascular system - phlebitis of superficial veins, heart rhythm disturbance, hot flashes;
• digestion - bloating, dry mouth, diarrhea, dyspepsia, flatulence, colic, gastrointestinal bleeding, nausea with vomiting;
• musculoskeletal system - muscle spasms, arthralgia;
• others - swelling of the larynx, allergies, fever, flu-like symptoms, sweating, urinary tract infections.

Essentiale forte

These are brown capsules. The active component of Essentiale forte - essential phospholipids - starts regeneration processes, normalizes metabolism and stops the replacement of healthy hepatocytes with connective tissue. Auxiliary components are:

• gelatin;
• purified water;
• ethanol 96%;
• α-tocopherol;
• castor oil;
• soybean oil;
• titanium dioxide;
• sodium lauryl sulfate.

Tablets are prescribed for recovery from toxicosis in pregnant women, chronic hepatitis, fatty liver degradation, cirrhosis, as an adjuvant therapy for psoriasis, and radiation syndrome. Essentiale forte should be taken with meals 2 capsules 2-3 times a day. The duration of treatment is 3 months, if necessary, can be repeated. Essentiale is well tolerated by the body, only occasionally causing stool upset. Essentiale has no serious contraindications.

Liv 52

This is a combined medicine to restore the functionality of the hepatic gland. The composition of Liv 52 consists entirely of vegetable raw materials:

• caper powder and common chicory;
• iron oxide;
• black nightshade;
• terminalia arjuna;
• cassia western;
• common yarrow;
• Gallic tamarix;
• eclipta white;
• medicinal fumes;
• Ceylon pig;
• medicinal emblic;
• seed radish.

Liv 52 has antitoxic, choleretic, anti-inflammatory, hepatoprotective effects. The components of the composition restore intracellular processes and protein synthesis. Due to such positive properties, a homeopathic remedy is prescribed for:

• different types of hepatitis (drug, toxic, viral);
• cholecystitis;
• fatty hepatosis;
• violations of the outflow of bile;
• fibrosis;
• biliary dyskinesia;
• cholangitis;
• for the prevention of alcohol abuse.

Liv 52 is available without a prescription. Adults need to take 2-3 tablets up to three times a day, children - 1 tablet 2-3 times a day. The duration of drug therapy is determined by the doctor. The drug is well tolerated by patients, only sometimes causing allergic reactions or dyspepsia. Liv 52 is prescribed with caution to patients with acute inflammation of the gastrointestinal tract (gastrointestinal tract).

The drug to restore the functionality of the liver is produced in capsules of 30 pieces or dragees of 80-180 pieces. The active component of the capsules is a dry extract of milk thistle fruits, dragees - silymarin. The pharmacodynamics and pharmacokinetics of the drug have not been fully studied, but it is known that the drug has a membrane-stabilizing effect and an antioxidant effect, and is able to improve blood microcirculation.

Karsil is used to prevent liver damage with prolonged use of alcohol or drugs. As part of complex therapy, capsules are prescribed for:

• chronic hepatitis of non-viral nature;
• cirrhosis;
• steatosis of alcoholic or non-alcoholic etiology;
• recovery of the body after acute hepatitis;
• toxic cell damage.

Karsil rarely causes adverse reactions. Contraindicated in case of hypersensitivity to components from the composition, lactase deficiency, celiac disease. The dosage depends on the form of release:

• capsules - for severe lesions, take 1 piece 3 times a day, for pathologies of moderate severity - 2 times a day;
• dragee - 1 or 2 pieces 3 times a day;
• the duration of drug treatment is 90 days.

Ovesol

The drug is one of the natural dietary supplements. Ovesol contains natural components that have anti-inflammatory, detoxifying, restorative effects - this is an extract of sowing oats, turmeric, immortelle flowers, peppermint. Bioadditive carefully "washes" the liver, reduces stagnation of bile, reduces the chance of cholelithiasis.

Tablets can cause allergies, are contraindicated in people with hypersensitivity to one or more components. With caution, Ovesol is prescribed to patients with bending of the gallbladder or cholelithiasis. According to the instructions, it is necessary to take dietary supplements for 20 days twice a day, 1 tablet. The course must be repeated 3-4 times a year.

Phosphogliv

This combined medicine is able to stabilize the membranes of liver cells, protect the organ from negative effects, and relieve inflammation. Phosphogliv is available in the form of gelatin capsules of 50 pieces with several active ingredients - phospholipids and sodium glycyrrhizinate. Auxiliary substances are:

• microcrystalline cellulose;
• sodium carbonate;
• calcium stearate;
• talc;
• silica;
• aerosil;
• titanium dioxide.

Capsules are taken orally during meals, without chewing. Recommended dosage - 2 pcs. three times a day. The duration of rehabilitation therapy can be up to 6 months. Phosphogliv often provokes allergic reactions, rarely causes hypertension, swelling of soft tissues. From the use of tablets to restore the liver must be abandoned:

• people with hypersensitivity to the composition;
• pregnant women;
• nursing mothers;
• patients with antiphospholipid syndrome;
• children under 12 years of age.

Gepabene

Combined agents restore bile secretion, relieve spasm of the gallbladder, and have hepatoprotective properties. One capsule contains many active ingredients - dry extract of fume, protopin, milk thistle fruit, silymarin. Excipients:

• magnesium stearate;
• microcrystalline cellulose;
• silica;
• corn starch;
• macrogol;
• gelatin;
• povidone.

The drug should be taken orally during meals. To restore the functionality of the hepatic gland, doctors prescribe 1 capsule 3 times a day. Duration is selected individually. Gepabene can rarely provoke an allergic reaction or cause a laxative effect. It is contraindicated:

• adolescents who have not reached the age of majority;
• patients with active forms of biliary tract diseases;
• with increased sensitivity of the patient to the composition of the drug.

The drug is produced in the form of capsules with the active ingredient - ursodeoxycholic acid. Ursofalk reduces the tendency to form stones in the bile ducts, helps to dissolve cholesterol plaques. The auxiliary components are:

• magnesium stearate;
• colloidal silicon dioxide;
• corn starch;
• gelatin;
• titanium dioxide;
• completed.

Ursofalk must be taken at bedtime in accordance with weight: 2 capsules for patients weighing up to 60 kg, 3 for patients weighing up to 80 kg, 4 pieces for patients weighing up to 100 kg. The duration of therapy is 6-12 months. Ursofalk is not recommended by the manufacturer for patients with acute inflammatory diseases of the gallbladder, blockage of the ducts. Ursofalk is able to provoke the appearance of:

• nausea;
• pain in the abdomen or right hypochondrium;
• diarrhea;
• increased activity of hepatic transaminases;
• allergic reactions.

Galstena

A homeopathic remedy with a mild hepatoprotective, antispasmodic, anti-inflammatory and choleretic effect is available in the form of tablets. The main active ingredients are extracts of milk thistle, medicinal dandelion, large celandine, phosphorus, sodium sulfate. Galstena is prescribed to restore the organ, with diseases of the gallbladder or pancreas.

Galstena can rarely provoke the appearance of increased salivation. The drug is not prescribed for alcohol dependence, hypersensitivity to the components. The drug is taken half an hour or an hour before meals in dosages depending on the diagnosis and age of the patient:

• With hepatitis, hepatosis or pancreatitis: children under 12 years of age are prescribed ½, adults - 1 tablet. The duration of therapy before recovery is 3 months, the frequency of use is 3 times / day.
• In chronic cholecystitis, cholelithiasis: children - ½ tab., adults - 1 tablet. The frequency of admission is 3 times / day, the duration of therapy is 1 month.

Hofitol

The choleretic agent has the ability to increase diuresis, has a pronounced hepatoprotective effect, reduces blood azotemia, and intensively removes urea. Hofitol refers to homeopathic remedies. It contains only one active ingredient - an extract of fresh leaves of the field artichoke. Hofitol is available in the form of tablets of 60 pieces per pack.

Adults are prescribed 2-3 tablets. 3 times a day before meals, children from 6 years old - 1-2 tab. The course of drug therapy is 3 months. Hofitol is well tolerated by patients, but can rarely cause minor allergic reactions or diarrhea. From taking pills to restore the liver will have to be abandoned when:

• acute diseases of the biliary or urinary tract;
• the presence of kidney stones;
• obstruction of the bile ducts.

tsikvalon

It is a synthetic drug developed on the basis of a single active ingredient - tsikvalon. The medicine is produced in the form of tablets for liver restoration with anti-inflammatory properties. Tsikvalon:

1. stimulates the secretion of bile;
2. reduces the severity of inflammatory processes;
3. relieves pain in diseases of the gallbladder;
4. prevents bloating;
5. eliminates fermentation in the intestines, normalizes stool.

Tsikvalon is prescribed for cholecystitis, cholangitis, cholelithiasis in dosages per gram 3-4 times a day. The course of treatment is 3-4 weeks (if necessary, it can be repeated in a month). Tsikvalon is contraindicated in case of blockage of the bile ducts. Tablets are well tolerated by patients and only occasionally can provoke a feeling of heaviness or a bitter taste in the mouth.

The phospholipid preparation has hepatoprotective properties, stabilizes cell membranes, activates tissue regeneration processes, inhibits collagen synthesis, and reduces cholesterol levels. The composition of tablets for liver restoration Rezalut Pro:

• phospholipids from soy lecithin;
• glycerol mono- or dialconate;
• soybean oil;
• α-tocopherol;
• gelatin.

Tablets should be taken 2 pieces 3 times a day before meals. The terms of rehabilitation therapy are selected for each patient individually. Rezalut pro is not prescribed to patients with antiphospholipid syndrome. With prolonged use, the drug provokes side effects from the systems:

• digestion - diarrhea, nausea, stomach discomfort;
• hematopoiesis - violation of the menstrual cycle in women, petechial rash;
• allergic reactions - urticaria.

Osalmid

The choleretic agent stimulates the formation and outflow of bile, has analgesic and anti-inflammatory properties, and normalizes the level of bilirubin. Osalmid is available in white or almost white powder, soluble in water. Take the drug inside 250-500 mg 3 times a day for up to 20 days. Osalmid can very rarely provoke diarrhea or allergies. Reception of the powder is contraindicated in:

• hypersensitivity;
• acute inflammation of the liver gland;
• dystrophic processes of soft tissues.

How to choose liver recovery pills

The list of hepatoprotectors offered by pharmaceutical companies is very wide, so it is often difficult for a patient to choose the best medicine. The fundamental factors are often the reviews of other patients, the price of the medicine, the proven effectiveness, but for liver diseases it is important to follow only one rule - the choice of medications should be made only by a doctor. Otherwise, the situation may worsen.

After alcohol

Drug treatment after severe alcohol intoxication is possible only after the patient completely refuses further use of alcoholic beverages. Homeopathic medicines, herbal remedies based on milk thistle, burdock root, and elecampane are considered the safest pharmaceutical products. They have a minimum of side effects and are used as a food supplement. Gepabene, Heptral, restorative Dipana, HepatoTransit, Tykveol have cleansing properties.

Hepatoprotectors for children

The list of drugs that are allowed for a child is not very long. Treatment of liver diseases in childhood must necessarily take place under the supervision of an experienced pediatrician or attending physician. Appointments:

1. From the age of one year it is allowed to use Galstena, Hepel.
2. Children who have reached the age of three may be prescribed Essentiale Forte, Antral.
3. After five years, Karsil, Gepabene, Ursosan are allowed.

With cirrhosis of the liver

Hepatotropic drugs will not allow the liver to collapse, restore its functionality as much as possible, and prevent the replacement of healthy cells with fibrous tissue in cirrhosis. At the initial stage of the disease, patients are prescribed a special diet and taking vitamin complexes. If the disease has entered the active phase, the treatment is supplemented with essential phospholipids, herbal medicines with milk thistle or artichoke - these are Karsil, Lipolyic acid, Phosphogliv.

With hepatitis

Hepatoprotectors are often prescribed as adjuvant therapy for hepatitis, but the main treatment is carried out with special antiviral agents. Preparations for the liver help restore its functionality, protect against the damaging effects of exogenous or endogenous factors, and accelerate the regeneration of its cells. Hepatitis is often prescribed:

• Ursoliv;
• Hofitol;
• Gepabene;
• Essentiale.

From fatty liver

Treatment of fatty hepatosis necessarily includes dieting, taking vitamin complexes and drugs with an antifibrotic effect:

• drugs with flavonoids - milk thistle tablets, Karsil, Silibor, Gepabene, Liv 52;
• hepatoprotectors with active ingredients of animal origin - Sirepar, Hepatostan;
• drugs with phospholipids - Essentiale, Essliver;
• preparations based on urodeoxycholic acid - Ursohol.

Hepatoprotectors while taking antibiotics

To prevent drug intoxication, drugs are prescribed to restore hepatic functionality with a minimum of contraindications and side effects. These are inexpensive hepatoprotectors with a strong cleansing function - Liv 52, Ovesol, Gepabene, Essentiale. To enhance the effect of these drugs, the doctor may prescribe Allochol, Essliver, HeptraLight.

Price

Most hepatoprotectors are available without a doctor's prescription. They can be bought at any pharmacy or ordered through an online store. The cost of the medicine will depend on its volume, manufacturer, pharmacy pricing and your region of residence. The average price of tablets for liver restoration in Moscow.